Description

1-Bromo-2,3-Dichloro-5-Fluorobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an invaluable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in fluorinated and halogenated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the specific halogen pattern confers desired biological activity.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating complex molecular architectures in academic and industrial R&D labs.

Basic Information

Product Name	1-Bromo-2,3-Dichloro-5-Fluorobenzene
CAS No.	1000577-58-1
Molecular Formula	C6H2BrCl2F
Molecular Weight	243.89 g/mol
Synonyms	2,3-Dichloro-5-fluorobromobenzene; 5-Fluoro-2,3-dichlorobromobenzene; Benzene, 1-bromo-2,3-dichloro-5-fluoro-; 1-Bromo-2,3-dichloro-5-fluorobenzol; 2-Bromo-1,3-dichloro-4-fluorobenzene (isomer); BDFB (abbreviation); 5-Fluoro-1-bromo-2,3-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3-Dichloro-5-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.