Description

(2-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a trifluoromethyl group and a carboxylic acid moiety, makes it an essential intermediate for creating compounds with enhanced biological activity and metabolic stability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services and scale-up production under cGMP for clinical trial materials.

Basic Information

Product Name	(2-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid
CAS No.	1000568-14-8
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(3-Pyridinyl)-2-(trifluoromethyl)acetic Acid; 2-(Trifluoromethyl)nicotinicacetic Acid; [2-(Trifluoromethyl)pyridin-3-yl]acetic Acid; 3-Carboxymethyl-2-trifluoromethylpyridine; α-(2-Trifluoromethyl-3-pyridyl)acetic Acid; (2-Trifluoromethyl-3-pyridinyl)acetic Acid; 2-(2-(Trifluoromethyl)pyridin-3-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our production of (2-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive identity confirmation and impurity profiling. A Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.