Description

(6-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which is strategically positioned to impart desirable properties like enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylpyridine moiety contributes to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(6-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid
CAS No.	1000565-32-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(6-(Trifluoromethyl)pyridin-2-yl)acetic acid; [6-(Trifluoromethyl)-2-pyridyl]acetic Acid; 2-Pyridineacetic acid, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)pyridine-2-acetic acid; (6-Trifluoromethyl-2-pyridyl)acetic Acid; α-Carboxymethyl-6-trifluoromethylpyridine; 6-Trifluoromethyl-2-pyridylacetic Acid
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can support documentation for use under cGMP, ISO, or other relevant quality frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.