Description

2-(2-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine is a high-value, fluorinated pyridine derivative building block essential for modern synthetic chemistry. This compound matters because its unique trifluoromethylpyridine-ethylamine scaffold is critical for introducing specific physicochemical properties into target molecules, enhancing their metabolic stability and bioavailability. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated polymers and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and fluorescent tags used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(2-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine
CAS No.	1000539-32-1
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	2-(2-(Trifluoromethyl)pyridin-3-yl)ethan-1-amine; 3-(2-Aminoethyl)-2-(trifluoromethyl)pyridine; 2-(2-Trifluoromethyl-3-pyridyl)ethylamine; 2-(3-Pyridyl)-2-trifluoromethylethylamine; 2-(2-Trifluoromethylpyridin-3-yl)ethanamine; 2-(2-Trifluoromethyl-3-pyridinyl)ethylamine; 2-(2-Trifluoromethyl-3-pyridyl)ethylamine
EINECS	Contact for details

Quality Control

Our 2-(2-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.