Description

3-Pyridineacetonitrile, 2-(Trifluoromethyl)- is a high-value, fluorinated pyridine derivative that serves as a critical synthetic intermediate. This compound matters for its unique trifluoromethylpyridine scaffold, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Pyridineacetonitrile, 2-(Trifluoromethyl)-
CAS No.	1000529-97-4
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	2-(Trifluoromethyl)-3-pyridineacetonitrile; 2-(Trifluoromethyl)nicotinonitrile; 3-Cyano-2-(trifluoromethyl)pyridine; (2-(Trifluoromethyl)pyridin-3-yl)acetonitrile; α-Pyridin-3-yl-2-(trifluoromethyl)acetonitrile; 2-Trifluoromethyl-3-cyanopyridine; 3-Pyridineacetonitrile, α-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Pyridineacetonitrile, 2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.