Description

(4-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a trifluoromethylpyridine moiety, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at pharmaceutical R&D and agrochemical manufacturers seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Precursor: Intermediate for synthesizing functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	(4-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid
CAS No.	1000515-78-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(4-(Trifluoromethyl)pyridin-2-yl)acetic acid; [4-(Trifluoromethyl)-2-pyridinyl]acetic Acid; 4-(Trifluoromethyl)picolinic Acid derivative; α-Carboxy-4-(trifluoromethyl)-2-picoline; (4-Trifluoromethyl-2-pyridyl)acetic Acid; TFMPAA; 2-Pyridineacetic acid, 4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (4-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of our R&D and manufacturing clients. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.