Description

2-Methyl-5-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. Its molecular structure, featuring both a nitrile group and a trifluoromethyl substituent, makes it a critical intermediate for synthesizing complex molecules with enhanced properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions, cyanoalkylations, and as a ligand precursor in organometallic chemistry.
• Advanced Polymer Chemistry: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing material properties like chemical resistance and thermal stability.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1000513-69-8
Molecular Formula	C10H8F3N
Molecular Weight	199.17 g/mol
Synonyms	2-Methyl-5-(trifluoromethyl)benzyl cyanide; [2-Methyl-5-(trifluoromethyl)phenyl]acetonitrile; α-Tolunitrile, 2-methyl-5-(trifluoromethyl)-; 2-(2-Methyl-5-(trifluoromethyl)phenyl)acetonitrile; 5-(Trifluoromethyl)-o-tolylacetonitrile; 2-Methyl-α,α,α-trifluoro-m-toluonitrile
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-5-(Trifluoromethyl)Phenylacetonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with your specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.