Description

2-(3-(Trifluoromethyl)Pyridin-2-Yl)Acetonitrile is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a nitrile and a trifluoromethylpyridine moiety, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring specialty polymers and electronic chemicals.

Application

• Pharmaceutical Intermediates: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis, including cross-coupling reactions critical for fine chemical manufacturing.
• Material Science Research: Building block for novel fluorinated polymers, liquid crystals, and organic electronic materials that require specific solubility and electronic characteristics.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and diagnostics.

Basic Information

Product Name	2-(3-(Trifluoromethyl)Pyridin-2-Yl)Acetonitrile
CAS No.	1000512-60-6
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	2-(3-(Trifluoromethyl)-2-pyridinyl)acetonitrile; 2-(3-(Trifluoromethyl)pyridin-2-yl)ethanenitrile; 2-Pyridineacetonitrile, 3-(trifluoromethyl)-; (3-(Trifluoromethyl)pyridin-2-yl)acetonitrile; 2-(3-Trifluoromethyl-2-pyridyl)acetonitrile; α-(3-Trifluoromethyl-2-pyridyl)acetonitrile; 1000512-60-6
EINECS	Contact for details

Quality Control

Every batch of 2-(3-(Trifluoromethyl)Pyridin-2-Yl)Acetonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A Certificate of Analysis (COA) documenting results from GC/HPLC, NMR, and mass spectrometry is provided with each shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.