Description

(3,4-Dimethyl-Phenyl)-Methanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the (3,4-dimethylphenyl)methanesulfonyl moiety, a functional group of significant interest in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on the synthesis of novel active ingredients, particularly in the development of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products, such as herbicides and fungicides.
• Chemical Biology Probes: Serves as a reagent for modifying proteins or other biomolecules to study biological pathways and interactions.
• Material Science: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	(3,4-Dimethyl-Phenyl)-Methanesulfonyl Chloride
CAS No.	1000350-12-8
Molecular Formula	C9H11ClO2S
Molecular Weight	218.70 g/mol
Synonyms	3,4-Dimethylbenzenemethanesulfonyl chloride; 1-(Chlorosulfonylmethyl)-3,4-dimethylbenzene; (3,4-Dimethylphenyl)methanesulfonyl chloride; α-Chlorosulfonyl-3,4-dimethyltoluene; 3,4-Dimethylbenzylsulfonyl chloride; (3,4-Xylyl)methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our (3,4-Dimethyl-Phenyl)-Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.