Description

2-Fluoro-5-Methylsulfonyl-3-Nitrotoluene is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique molecular structure, featuring fluorine, methylsulfonyl, and nitro substituents, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its fluorinated aromatic core.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where the nitro and sulfone groups contribute to color fastness and stability.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Fluoro-5-Methylsulfonyl-3-Nitrotoluene
CAS No.	1000339-67-2
Molecular Formula	C8H8FNO4S
Molecular Weight	233.22 g/mol
Synonyms	1-Fluoro-2-methyl-4-(methylsulfonyl)-5-nitrobenzene; Toluene, 2-fluoro-5-methylsulfonyl-3-nitro-; 2-Fluoro-3-nitro-5-(methylsulfonyl)toluene; 5-(Methylsulfonyl)-2-fluoro-3-nitrotoluene; 2-Methyl-1-fluoro-4-(methylsulfonyl)-5-nitrobenzene; CAS 1000339-67-2
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methylsulfonyl-3-Nitrotoluene is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.