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1-Bromo-3-Dichloromethyl-5-Fluorobenzene CAS NO 1000339-58-1


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CAS No.:1000339-58-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Bromo-3-Dichloromethyl-5-Fluorobenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a reactive dichloromethyl group, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of fluorinated bioactive molecules.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
  • Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and other advanced organic materials with tailored properties.
  • Chemical Derivatization: The reactive dichloromethyl group allows for further functionalization, making it a versatile starting point for custom synthesis projects.

Basic Information

Product Name 1-Bromo-3-Dichloromethyl-5-Fluorobenzene
CAS No. 1000339-58-1
Molecular Formula C7H4BrCl2F
Molecular Weight 258.92 g/mol
Synonyms 3-Bromo-5-(dichloromethyl)-1-fluorobenzene; 5-Bromo-3-(dichloromethyl)fluorobenzene; 1-Fluoro-3-bromo-5-(dichloromethyl)benzene; Benzene, 1-bromo-3-(dichloromethyl)-5-fluoro-; 1000339-58-1; 3-(Dichloromethyl)-5-bromofluorobenzene
EINECS Contact for details

Quality Control

Our 1-Bromo-3-Dichloromethyl-5-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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