Description

Dha-Paclitaxel is a semi-synthetic derivative of the potent anticancer agent Paclitaxel, designed to enhance solubility and therapeutic efficacy. This compound is a critical intermediate in the development of advanced pharmaceutical formulations, particularly targeted drug delivery systems. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in oncology drug discovery and the production of next-generation chemotherapeutic agents.

Application

• As a key pharmaceutical intermediate in the synthesis of novel, water-soluble paclitaxel prodrugs.
• In oncology research for studying structure-activity relationships and developing targeted cancer therapies.
• For the formulation of liposomal and nanoparticle-based drug delivery systems to improve biodistribution and reduce side effects.
• In the development of combination therapies where enhanced solubility of the active ingredient is required.
• As a reference standard in analytical method development and quality control for paclitaxel-related compounds.

Basic Information

Product Name	Dha-Paclitaxel
CAS No.	199796-52-6
Molecular Formula	C47H51NO14
Molecular Weight	853.91 g/mol
Synonyms	2'-Docosahexaenoyl Paclitaxel; DHA-Paclitaxel; Docosahexaenoyl Paclitaxel; Paclitaxel 2'-docosahexaenoate; 2'-(4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoyl)paclitaxel; Taxol DHA conjugate; DHA-Taxol; C47 Paclitaxel Derivative
EINECS	Contact for details

Quality Control

Our Dha-Paclitaxel is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere or with desiccant to prevent moisture uptake. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.