Description

-Cyclodextrin Phosphate Sodium Sa is a chemically modified cyclodextrin derivative where phosphate sodium salt groups are introduced onto the cyclodextrin backbone. This modification significantly enhances its solubility and stability, making it a superior solubilizing and stabilizing agent for hydrophobic compounds. It is a critical advanced excipient for the pharmaceutical industry, particularly valuable in drug formulation to improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Formulations: As a solubility enhancer and stabilizer for poorly water-soluble drugs in oral, injectable, and topical preparations.
• Drug Delivery Systems: For constructing novel drug delivery platforms, including nanoparticles and targeted release systems, leveraging its host-guest complexation properties.
• Analytical Chemistry: Used as a chiral selector or mobile phase additive in chromatography (HPLC, CE) for the separation of enantiomers and isomers.
• Cosmetics & Personal Care: To encapsulate fragrances, vitamins, or active ingredients, improving their stability, shelf-life, and controlled release in creams and lotions.
• Food & Nutraceuticals: For the encapsulation of flavors, colors, and bioactive compounds (e.g., vitamins, fatty acids) to mask odors, enhance stability, and improve bioavailability.
• Chemical Research: As a molecular host in supramolecular chemistry for catalysis, sensor development, and material science applications.

Basic Information

Product Name	-Cyclodextrin Phosphate Sodium Sa
CAS No.	199684-60-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sodium -Cyclodextrin Phosphate; Phosphorylated -Cyclodextrin Sodium Salt; -CD-PO4Na; Cyclodextrin Phosphate Sodium Salt; Heptakis(6-O-phosphono)- -cyclodextrin sodium salt; 6^A-Phosphate- -cyclodextrin sodium salt; -Cyclodextrin Heptakis(phosphate) Sodium Salt; -Cyclodextrin Phosphoric Acid Ester Sodium Salt
EINECS	Contact for details

Quality Control

Our -Cyclodextrin Phosphate Sodium Sa is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which include key parameters such as assay, degree of substitution, residual solvents, and microbiological data. Specifications can be aligned with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which can affect product performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Degree of Substitution	Contact for details
Water Content (KF)	≤ 10.0%
Residue on Ignition	Contact for details
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Conforms to Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.