Description

3-Fluoro-4-Methylquinolin-2(1H)-One is a high-value, fluorinated quinolinone derivative, a crucial building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a privileged structure for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials and functional dyes.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	3-Fluoro-4-Methylquinolin-2(1H)-One
CAS No.	198831-76-4
Molecular Formula	C₁₀H₈FNO
Molecular Weight	177.18 g/mol
Synonyms	3-Fluoro-4-methyl-1H-quinolin-2-one; 3-Fluoro-4-methyl-2(1H)-quinolinone; 4-Methyl-3-fluoroquinolin-2(1H)-one; 2(1H)-Quinolinone, 3-fluoro-4-methyl-; 3-Fluoro-4-methyl-2-quinolone; 3-Fluoro-4-methylcarbostyril
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.