Description

2-Cyano-5-Methylbenzenesulfonyl Chloride is a versatile and high-value sulfonyl chloride derivative, primarily utilized as a key synthetic intermediate in advanced organic synthesis. Its core value proposition lies in its reactive sulfonyl chloride group, which enables efficient sulfonamide bond formation, a critical step in constructing complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a crucial building block for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for creating sulfonamide-based pharmacophores with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the benzenesulfonyl moiety can contribute to biological activity.
• Functional Material Precursor: Serves as a starting material for synthesizing specialized dyes, pigments, and polymers that require specific sulfonamide linkages for enhanced properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical reactions involving sulfonylation.
• Ligand and Catalyst Design: Useful for constructing complex organic ligands and catalysts where the cyano and sulfonyl groups can be further modified to tune electronic and steric properties.

Basic Information

Product Name	2-Cyano-5-Methylbenzenesulfonyl Chloride
CAS No.	197960-31-9
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	5-Methyl-2-cyanobenzenesulfonyl chloride; 2-Cyano-5-methylbenzene-1-sulfonyl chloride; 2-Cyano-5-methylphenylsulfonyl chloride; 5-Methyl-2-cyanophenylsulfonyl chloride; 2-Cyanotoluene-5-sulfonyl chloride; 5-Methyl-2-cyanobenzenesulphonyl chloride; Toluene-2-cyano-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-5-Methylbenzenesulfonyl Chloride undergoes rigorous analytical testing to ensure it meets the high-purity standards required for synthetic applications. Our quality assurance protocols include identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.