Description

Heptakis(6-o-Sulfo)-(Beta)-Cyclodextrin is a highly sulfated derivative of β-cyclodextrin, engineered to enhance solubility and binding affinity for a wide range of guest molecules. This compound is critical for applications requiring strong anionic character and complexation capabilities in aqueous environments. It is primarily utilized by researchers and manufacturers in the pharmaceutical, analytical chemistry, and biotechnology sectors for drug delivery, chiral separation, and solubility enhancement.

Application

• Pharmaceutical Solubilization & Drug Delivery: Acts as a superior solubilizing and stabilizing agent for poorly water-soluble active pharmaceutical ingredients (APIs).
• Chiral Separation & Analytical Chemistry: Serves as a chiral selector in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for the separation of enantiomers.
• Biotechnology & Protein Stabilization: Used to stabilize proteins and enzymes in formulation buffers, preventing aggregation and denaturation.
• Catalysis & Chemical Synthesis: Functions as a water-soluble host for catalysts, facilitating reactions in aqueous media and improving selectivity.
• Environmental & Sensor Applications: Employed in sensor technologies and extraction processes for the detection and removal of specific organic contaminants.

Basic Information

Product Name	Heptakis(6-o-Sulfo)-(Beta)-Cyclodextrin
CAS No.	197587-31-8
Molecular Formula	C42H56O56S7
Molecular Weight	Approx. 1497.3 g/mol
Synonyms	Heptakis(6-O-sulfo)-β-cyclodextrin; β-Cyclodextrin heptakis(hydrogen sulfate); Sulfated β-cyclodextrin (heptakis, 6-O); SBE-β-CD (Heptakis); 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-sulfo-β-cyclodextrin; β-Cyclodextrin Sulfate Sodium Salt (Heptakis); 197587-31-8
EINECS	Contact for details

Quality Control

Our Heptakis(6-o-Sulfo)-(Beta)-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, degree of substitution (DS) analysis, and impurity profiling, to ensure consistent performance and high purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which can affect performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (DS)	6.5 - 7.5
Water Content (KF)	≤ 8.0 %
Residue on Ignition (Sulfated Ash)	≤ 20.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Bacterial Endotoxins	< 20 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.