Description

Sb 220025 Trihydrochloride is a high-purity organic salt compound, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. This compound is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Drug Discovery: Used in medicinal chemistry for the design and optimization of new chemical entities with potential therapeutic activity.
• Biochemical Research: Serves as a reagent or precursor in studies investigating biological pathways and mechanisms of action.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes during pharmaceutical process development.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in laboratory settings.

Basic Information

Product Name	Sb 220025 Trihydrochloride
CAS No.	197446-75-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SB-220025 Trihydrochloride; SB220025 Trihydrochloride; 1,5-Dihydro-3-[4-(1H-imidazol-1-yl)phenyl]-6-methyl-2H-pyrrolo[3,2-f]quinazoline-2,4(3H)-dione trihydrochloride; Tandospirone trihydrochloride (common alias); 5-HT1A receptor ligand intermediate; Azapirone derivative trihydrochloride
EINECS	Contact for details

Quality Control

Our Sb 220025 Trihydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable for the manufacture of pharmaceutical intermediates, and specifications can be aligned with client requirements for advanced R&D use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.