Description

Spisulosine is a potent and selective marine-derived sphingosine-like compound with significant biological activity. This molecule is of high interest for its role in disrupting actin cytoskeleton dynamics and inducing apoptosis in specific cell types. It serves as a critical research-grade biochemical for scientists in oncology, cell biology, and pharmacology. The compound, identified as CAS NO 196497-48-0, is essential for advancing studies in cancer research and novel therapeutic pathway exploration.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of actin cytoskeleton disruption and programmed cell death (apoptosis).
• Oncology Research: Investigated for its potential anti-cancer properties and mechanism of action in various cancer cell line models.
• Pharmacology & Drug Discovery: Serves as a lead compound or molecular tool for screening and developing novel therapeutic agents.
• Cell Signaling Studies: Employed to study sphingolipid-mediated signaling pathways and their impact on cellular function and survival.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental biological and chemical research.
• Biotech & Pharmaceutical Development: Utilized in preclinical research for target validation and proof-of-concept studies.

Basic Information

Product Name	Spisulosine
CAS No.	196497-48-0
Molecular Formula	C₁₉H₃₉NO₂
Molecular Weight	313.52 g/mol
Synonyms	ES-285; (2S,3R)-2-Amino-3-hydroxyoctadecane; Spisulosine (ES-285); ES 285; 1-Amino-2-hydroxyoctadecane; Spisulosine hydrochloride; (2S,3R)-2-Amino-1,3-octadecanediol; Marine sphingosine analog
EINECS	Contact for details

Quality Control

Our Spisulosine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided, documenting purity, assay, and relevant physicochemical parameters to meet the exacting standards of the research community.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.