Description

Heptakis(2,3-Di-O-acetyl-6-O-sulfo)-β-cyclodextrin is a chemically modified, anionic cyclodextrin derivative designed for advanced molecular recognition and separation science. This compound matters for its unique ability to form selective inclusion complexes, significantly enhancing solubility, stability, and chiral resolution of guest molecules. It is essential for researchers and manufacturers in the pharmaceutical, analytical chemistry, and biotechnology sectors who require high-purity chiral selectors and complexing agents.

Application

• Chiral Separation in HPLC & CE: Serves as a chiral selector in the mobile phase or as a capillary electrophoresis buffer additive for the resolution of enantiomers in pharmaceutical analysis.
• Pharmaceutical Solubilization & Stabilization: Used to enhance the aqueous solubility, bioavailability, and chemical stability of poorly soluble active pharmaceutical ingredients (APIs).
• Analytical Method Development: A key reagent for developing and validating analytical methods for the quantification of specific compounds via complexation.
• Biochemical Research: Employed in studies of protein-ligand interactions, enzyme inhibition, and as a model system for supramolecular chemistry research.
• Catalysis & Synthesis: Acts as a supramolecular catalyst or a reaction medium modifier in organic synthesis to improve selectivity and yield.
• Food & Flavor Industry: Potential use for the encapsulation, protection, and controlled release of sensitive flavors, fragrances, or nutrients.

Basic Information

Product Name	Heptakis(2,3-Di-O-acetyl-6-O-sulfo)-β-cyclodextrin
CAS No.	196398-66-0
Molecular Formula	C70H98O56S7
Molecular Weight	~ 2363.7 g/mol (as sodium salt)
Synonyms	Sulfobutyl Ether β-Cyclodextrin, Acetylated; Heptakis(2,3-di-O-acetyl-6-O-sulfo)-β-CD; SBE-β-CD (Acetylated); β-Cyclodextrin, heptakis(2,3-di-O-acetyl-6-O-sulfo)-; 6A-O-Sulfo-2A,3A-di-O-acetyl-β-cyclodextrin (heptakis); Anionic Acetylated β-Cyclodextrin; CAS 196398-66-0
EINECS	Contact for details

Quality Control

Our Heptakis(2,3-Di-O-acetyl-6-O-sulfo)-β-cyclodextrin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, consistent substitution degree, and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing identity, purity (HPLC), sulfonation degree, acetyl content, and residual solvents are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (Sulfobutyl)	~6.0 - 7.0
Acetyl Content	~14 acetyl groups per molecule
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
pH (1% Solution)	5.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.