Description

17-Trifluoromethylphenyl Trinor Prostaglandin F2α Methyl Ester is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural specificity, enabling precise biological activity modulation in targeted therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel ophthalmic solutions, dermatological treatments, and other specialized medicinal products.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Research: Used in R&D for next-generation glaucoma and ocular hypertension treatments targeting the FP receptor.
• Dermatological Development: Investigated for applications in hair growth modulation and skin condition therapies.
• Biochemical Research: Serves as a precise tool compound for studying prostaglandin receptor (FP) signaling and function.
• Process Chemistry: Employed in route scouting and scale-up optimization for complex prostaglandin synthesis.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical manufacturing.

Basic Information

Product Name	17-Trifluoromethylphenyl Trinor Prostaglandin F2α Methyl Ester
CAS No.	195503-20-9
Molecular Formula	C27H33F3O5
Molecular Weight	494.55 g/mol
Synonyms	Fluprostenol Isopropyl Ester Related Compound; 17-Phenyl-13,14-dihydrotrinor Prostaglandin F2α Methyl Ester, 3-Trifluoromethyl Derivative; Travoprost Related Compound A; 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-(3-(trifluoromethyl)phenoxy)-1-pentenyl]cyclopentyl]-5-heptenoic Acid Methyl Ester; AL-6221; AFP-168; Prostaglandin F2α 17-Trifluoromethylphenyl Trinor Methyl Ester
EINECS	Contact for details

Quality Control

Our 17-Trifluoromethylphenyl Trinor Prostaglandin F2α Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.