Description

2,4-Bis(Trifluoromethyl)Benzyl Chloride is a high-value, multi-functional fluorinated aromatic building block. This compound is critical for introducing the benzyl chloride moiety with electron-withdrawing trifluoromethyl groups into target molecules, significantly altering their physicochemical properties. It is primarily sought after by R&D and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to produce specialty polymers with improved chemical resistance and thermal stability.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to construct complex fluorinated architectures.
• Dye & Pigment Intermediate: Employed in the production of high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Benzyl Chloride
CAS No.	195136-46-0
Molecular Formula	C9H5ClF6
Molecular Weight	262.58 g/mol
Synonyms	α-Chloro-2,4-bis(trifluoromethyl)toluene; 1-(Chloromethyl)-2,4-bis(trifluoromethyl)benzene; Benzene, 1-(chloromethyl)-2,4-bis(trifluoromethyl)-; 2,4-Bis(trifluoromethyl)benzyl chloride; (2,4-Bis(trifluoromethyl)phenyl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,4-Bis(Trifluoromethyl)Benzyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC analysis, is supplied with each shipment to guarantee traceability, consistency, and reliability for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.