Description

5-Bromo-1-Fluoro-2,3-Dimethylbenzene is a high-purity, halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on a dimethylbenzene core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro groups can enhance binding affinity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Fluorine Chemistry Building Block: The presence of fluorine makes it valuable for introducing fluorine atoms into target molecules, a common strategy in modern drug design to modulate properties like lipophilicity and metabolic stability.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways involving halogenated aromatics.

Basic Information

Product Name	5-Bromo-1-Fluoro-2,3-Dimethylbenzene
CAS No.	194805-16-8
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	2,3-Dimethyl-5-bromo-1-fluorobenzene; 1-Bromo-4-fluoro-2,3-dimethylbenzene; 5-Bromo-1-fluoro-2,3-xylene; 2,3-Dimethyl-1-fluoro-5-bromobenzene; 5-Bromo-2,3-dimethylfluorobenzene; 1-Fluoro-5-bromo-2,3-dimethylbenzene; 5-Bromo-2,3-dimethyl-1-fluorobenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Fluoro-2,3-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.