Description

Taxuspine X is a high-purity, semi-synthetic taxane derivative, a compound of significant interest in advanced pharmaceutical research and development. Its unique molecular structure makes it a valuable intermediate for the synthesis of novel therapeutic agents, particularly in oncology. This product is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation cancer treatments and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel taxane-based chemotherapeutic agents and prodrugs.
• Oncology Research: Used as a reference standard and active material in preclinical studies targeting microtubule stabilization and apoptosis.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of targeted cancer therapies.
• Biochemical Research: Employed in studies investigating cell cycle regulation, mitotic inhibition, and mechanisms of drug resistance.
• Fine Chemical Synthesis: An advanced intermediate for the production of high-value, complex organic molecules in contract manufacturing.
• Analytical Standard: Provides a certified reference material for quality control and analytical method development (HPLC, LC-MS) in pharmaceutical analysis.

Basic Information

Product Name	Taxuspine X
CAS No.	194782-02-0
Molecular Formula	C47H51NO14
Molecular Weight	853.91 g/mol
Synonyms	Taxuspine X; 10-Deacetyl-7-epitaxol; 10-Deacetyl-7-epipaclitaxel; 7-Epi-10-deacetylpaclitaxel; NSC 654663; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
EINECS	Contact for details

Quality Control

Every batch of Taxuspine X is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) that detail specifications including assay, related substances, and residual solvents, meeting the stringent requirements of pharmaceutical R&D. Our commitment to cGMP principles ensures a reliable supply of this critical intermediate for your development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the certificate of analysis. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept in a dry environment and opened under inert atmosphere when handling is required for extended periods.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.