Description

4-Fluoroisoquinoline-5-Sulfonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced synthetic chemistry. This compound is a critical building block for the development of novel pharmaceuticals and agrochemicals, enabling the introduction of the sulfonyl chloride functional group into complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments specializing in medicinal chemistry, process development, and the synthesis of biologically active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides and pesticides with tailored activity profiles.
• Chemical Biology Probes: Serves as a reactive handle for labeling proteins or creating activity-based probes for enzyme studies.
• Material Science: Building block for creating specialized polymers or functionalized surfaces with specific chemical properties.
• Sulfonamide Library Synthesis: Central reagent for the parallel or combinatorial synthesis of diverse sulfonamide libraries for high-throughput screening.

Basic Information

Product Name	4-Fluoroisoquinoline-5-Sulfonyl Chloride
CAS No.	194032-33-2
Molecular Formula	C9H5ClFNO2S
Molecular Weight	245.66 g/mol
Synonyms	5-Chlorosulfonyl-4-fluoroisoquinoline; 4-Fluoro-5-isoquinolinesulfonyl chloride; Isoquinoline-5-sulfonyl chloride, 4-fluoro-; 4-Fluoroisoquinoline-5-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoroisoquinoline-5-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.