Description

2,3,4-Trifluorotoluene is a high-purity fluorinated aromatic building block essential for advanced chemical synthesis. This compound is valued for its unique trifluoromethyl-substituted benzene structure, which imparts desirable electronic and steric properties to target molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution to introduce the trifluorotoluene moiety into complex molecules.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research programs exploring fluorine chemistry.

Basic Information

Product Name	2,3,4-Trifluorotoluene
CAS No.	193533-92-5
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1,2,3-Trifluoro-4-methylbenzene; 2,3,4-Trifluoromethylbenzene; α,α,α-Trifluoro-2,3,4-trimethylbenzene (incorrect but common misnomer); Toluene, 2,3,4-trifluoro-; 4-Methyl-1,2,3-trifluorobenzene; Benzene, 1-methyl-2,3,4-trifluoro-
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.25 g/mL
Refractive Index (n20D)	~1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.