Description

4-(4-Pyridyloxy)Benzenesulfonyl Chloride Hydrochloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to develop novel herbicides and fungicides by constructing sulfonamide linkages in active ingredients.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-(4-Pyridyloxy)Benzenesulfonyl Chloride Hydrochloride
CAS No.	192330-49-7
Molecular Formula	C11H9Cl2NO3S
Molecular Weight	322.16 g/mol
Synonyms	4-(Pyridin-4-yloxy)benzenesulfonyl chloride hydrochloride; 4-(4-Pyridyloxy)phenylsulfonyl chloride hydrochloride; 1-(4-Pyridyloxy)-4-chlorosulfonylbenzene hydrochloride; Benzenesulfonyl chloride, 4-(4-pyridinyloxy)-, hydrochloride; 4-Pyridin-4-yloxy-benzenesulfonyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Pyridyloxy)Benzenesulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.