Description

4-(2-Pyridyloxy)Phenylsulphonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is essential for introducing the 4-(2-pyridyloxy)phenylsulfonyl moiety, a functional group of significant interest in medicinal chemistry and materials science. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials. Due to its reactive nature, it requires careful handling and storage to maintain its integrity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Building block for creating functional polymers, ligands for metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Peptide Modification: Useful for the selective sulfonylation of amino acid side chains in peptide chemistry.
• Cross-coupling Reactions: Serves as an electrophilic coupling partner in various palladium-catalyzed cross-coupling reactions to form carbon-sulfur bonds.

Basic Information

Product Name	4-(2-Pyridyloxy)Phenylsulphonyl Chloride
CAS No.	192329-94-5
Molecular Formula	C11H8ClNO3S
Molecular Weight	269.70 g/mol
Synonyms	4-(Pyridin-2-yloxy)benzenesulfonyl chloride; 2-(4-Chlorosulfonylphenoxy)pyridine; 4-(2-Pyridyloxy)benzenesulfonyl chloride; 4-(2-Pyridinyloxy)benzenesulfonyl chloride; 192329-94-5; 4-(2-Pyridyloxy)phenyl sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Pyridyloxy)Phenylsulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and scale-up applications. We employ advanced analytical techniques, including HPLC, NMR, and IR spectroscopy, for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.