Description

(Z)-7-[(1S,2R,3R,5S)-3,5-Dihydroxy-2-(3-Oxooctyl)Cyclopentyl]Hept-5-Enoic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. Its precise stereochemistry and functional groups make it a critical building block for synthesizing bioactive molecules targeting specific physiological pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and life sciences industries, particularly those developing novel therapeutics in areas such as ophthalmology, cardiovascular medicine, and inflammation.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research and production of prostaglandin analogs for glaucoma treatment and other ocular conditions.
• Biochemical Research: Serves as a reference standard and a tool compound for studying prostaglandin receptors and signaling pathways in vitro and in vivo.
• Process Chemistry & Scale-Up: Employed in process development and optimization for the commercial manufacturing of prostaglandin derivatives.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects requiring high-stereochemical purity.

Basic Information

Product Name	(Z)-7-[(1S,2R,3R,5S)-3,5-Dihydroxy-2-(3-Oxooctyl)Cyclopentyl]Hept-5-Enoic Acid
CAS No.	191919-02-5
Molecular Formula	C20H34O5
Molecular Weight	354.48 g/mol
Synonyms	Prostaglandin F2α Ethanolamide Intermediate; Travoprost Intermediate; 13,14-Dihydro-15-keto-PGF2α Ethanolamide; (5Z)-7-[(1S,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-oxooctyl]cyclopentyl]hept-5-enoic Acid; AL-8810 Intermediate; 15-Keto-13,14-dihydro-PGF2α ethanolamide; Prostaglandin Analog Synthon; 191919-02-5
EINECS	Contact for details

Quality Control

Our (Z)-7-[(1S,2R,3R,5S)-3,5-Dihydroxy-2-(3-Oxooctyl)Cyclopentyl]Hept-5-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral methods for stereochemical confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.