Description

Ac-Ietd-Cho CAS NO 191338-86-0 is a specialized, high-purity chemical building block, specifically a protected peptide aldehyde. This compound matters as a critical intermediate in advanced pharmaceutical research and development, enabling the synthesis of complex molecules. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for applications in drug discovery, proteomics, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of protease inhibitors and other therapeutic peptides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to understand protein function.
• Drug Discovery: Employed in high-throughput screening and medicinal chemistry programs to develop new drug candidates targeting specific enzymes.
• Chemical Biology Tool: Serves as a molecular probe for studying apoptosis pathways and caspase activity in cellular systems.
• Peptide Synthesis: Acts as a crucial, protected aldehyde component in solid-phase and solution-phase peptide synthesis.

Basic Information

Product Name	Ac-Ietd-Cho CAS NO 191338-86-0
CAS No.	191338-86-0
Molecular Formula	C20H28N4O6
Molecular Weight	420.46 g/mol
Synonyms	Ac-Ile-Glu-Thr-Asp-CHO; Ac-IETD-CHO; Ac-IETD-aldehyde; Caspase-8 Inhibitor II; N-Acetyl-Ile-Glu-Thr-Asp-al; N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-L-aspartic acid aldehyde; Ac-Ile-Glu-Thr-Asp-H
EINECS	Contact for details

Quality Control

Our Ac-Ietd-Cho is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.