Description

Ro 32-3555 is a potent and selective inhibitor of matrix metalloproteinases (MMPs), specifically targeting collagenase-1 (MMP-1). This compound is a critical research tool for studying the role of MMPs in physiological and pathological processes, such as tissue remodeling, arthritis, and cancer metastasis. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and biochemical pathway analysis.

Application

• Biochemical Research: Used as a selective inhibitor to study the function and inhibition mechanisms of collagenase-1 (MMP-1) in enzymatic assays.
• Drug Discovery & Development: Serves as a reference compound and a lead structure in the development of novel therapeutics for diseases involving extracellular matrix degradation.
• Oncology Research: Investigated for its potential to inhibit tumor invasion and metastasis by blocking MMP-mediated pathways.
• Inflammatory Disease Models: Applied in research models for rheumatoid arthritis, osteoarthritis, and other conditions characterized by connective tissue breakdown.
• Cell Culture & In Vitro Studies: Utilized to modulate MMP activity in cell-based assays to understand cell migration and tissue remodeling.

Basic Information

Product Name	Ro 32-3555
CAS No.	190648-49-8
Molecular Formula	C₂₀H₂₈N₄O₄
Molecular Weight	388.46 g/mol
Synonyms	Ro-32-3555; Ro 32-3555; Trocade; (2R)-2-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-methylbutanamide; CAS 190648-49-8; MMP-1 Inhibitor; Collagenase-1 Inhibitor
EINECS	Contact for details

Quality Control

Our Ro 32-3555 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.