Description

Epoxycytochalasin C, 19,20- is a chemically modified derivative of the cytochalasin family, a group of potent fungal metabolites known for their ability to bind to actin filaments and disrupt cytoskeletal dynamics. This specific epoxidized analog is a critical research-grade biochemical tool used to study cell motility, morphology, and intracellular transport mechanisms with high specificity. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in cell biology, pharmacology, and cancer research.

Application

• Cytoskeleton Research: As a specific inhibitor of actin polymerization, used to investigate cell shape changes, division, and motility.
• Mechanistic Cell Biology Studies: Employed to probe the role of actin dynamics in processes like endocytosis, exocytosis, and organelle transport.
• Cancer Research: Used in vitro to study metastasis, invasion, and the effects of cytoskeletal disruption on cancer cell viability and proliferation.
• Pharmacological Profiling: Serves as a reference compound or a precursor in the development and screening of novel cytoskeletal-targeting therapeutic agents.
• Neuroscience Research: Applied in studies of growth cone guidance, synaptic plasticity, and neuronal morphology where actin dynamics are crucial.
• High-Content Screening (HCS): Utilized as a control or perturbagen in automated imaging assays to validate phenotypes related to cytoskeletal integrity.

Basic Information

Product Name	Epoxycytochalasin C, 19,20-
CAS No.	189351-79-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	19,20-Epoxycytochalasin C; 19,20-Epoxycytochalasin C (6CI); Cytochalasin C, 19,20-epoxide; (19S,20R)-19,20-Epoxycytochalasin C; Epoxycytochalasin C
EINECS	Contact for details

Quality Control

Our Epoxycytochalasin C, 19,20- is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation (e.g., by NMR, MS), and other relevant parameters is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The compound is moisture-sensitive (hygroscopic) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.