Description

3A-Amino-3A-Deoxy-(2As,3As)-γ-Cyclodextrin Hydrate is a chemically modified derivative of γ-cyclodextrin featuring a single amino group substitution, which introduces a reactive primary amine functionality onto the macrocyclic scaffold. This modification is critical for creating advanced host-guest complexes and serves as a versatile building block for further chemical derivatization, enabling precise molecular encapsulation and targeted delivery. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require specialized chiral selectors, solubility enhancers, or functionalized carrier systems. The compound is supplied as a hydrate to ensure stability.

Application

• Pharmaceutical Research & Development: As a chiral selector for the separation and analysis of enantiomers in drug discovery via capillary electrophoresis (CE) or HPLC.
• Drug Delivery Systems: Functionalization point for creating targeted drug conjugates or smart carrier systems that improve drug solubility, stability, and bioavailability.
• Chemical Synthesis: Acts as a novel scaffold or catalyst in supramolecular chemistry for constructing complex molecular architectures and facilitating asymmetric reactions.
• Analytical Chemistry: Used in the preparation of stationary phases for chiral chromatography columns and as an additive in run buffers for enantiomeric purity determination.
• Biomimetic Studies: Serves as a model for enzyme mimics and molecular recognition studies due to its defined cavity and modifiable functional group.
• Sensor Technology: Component in the development of chemical sensors and biosensors where the amino group allows for immobilization on surfaces or coupling with signaling molecules.

Basic Information

Product Name	3A-Amino-3A-Deoxy-(2As,3As)-γ-Cyclodextrin Hydrate
CAS No.	189307-64-0
Molecular Formula	C~48~H~79~NO~39~ · xH~2~O
Molecular Weight	~1144.1 g/mol (Anhydrous basis)
Synonyms	3^A^-Amino-3^A^-deoxy-γ-cyclodextrin hydrate; 3^A^-Amino-3^A^-deoxy-γ-cyclodextrin hydrate; 3-Amino-3-deoxy-γ-cyclodextrin; Mono(3-amino-3-deoxy)-γ-cyclodextrin; 3^A^-NH~2~-γ-CD; γ-Cyclodextrin, 3^A^-amino-3^A^-deoxy-, hydrate; 3^A^-Amino-3^A^-deoxy-(2^AS^,3^AS^)-γ-cyclodextrin hydrate
EINECS	Contact for details

Quality Control

Our 3A-Amino-3A-Deoxy-(2As,3As)-γ-Cyclodextrin Hydrate is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing key parameters such as assay (by HPLC), chiral purity, water content, and residual solvents. We support research and development with custom synthesis and purification services to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant in the storage environment. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% (by CE or HPLC)
Water Content (KF)	≤ 10.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.