Description

Methyl 2,6-Dichloro-5-Fluoronicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and dichloro-substituted pyridine core enhance bioactivity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, functionalized polymers, or advanced materials requiring fluorinated aromatic components.

Basic Information

Product Name	Methyl 2,6-Dichloro-5-Fluoronicotinate
CAS No.	189281-66-1
Molecular Formula	C7H4Cl2FNO2
Molecular Weight	224.02 g/mol
Synonyms	2,6-Dichloro-5-fluoronicotinic acid methyl ester; Methyl 2,6-dichloro-5-fluoropyridine-3-carboxylate; 5-Fluoro-2,6-dichloronicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 2,6-dichloro-5-fluoro-, methyl ester; Methyl 5-fluoro-2,6-dichloronicotinate
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Dichloro-5-Fluoronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.