Description

Anti-Caspase-7 is a potent and selective inhibitor of the caspase-7 enzyme, a key executioner protease in apoptotic pathways. This high-purity biochemical is essential for researchers and pharmaceutical developers investigating programmed cell death mechanisms and developing novel therapeutics for cancer and neurodegenerative diseases. It is a critical tool for target validation, high-throughput screening, and biochemical assay development in academic, biotechnology, and pharmaceutical R&D laboratories globally.

Application

• Apoptosis Research: Used as a specific inhibitor to elucidate the distinct roles of caspase-7 in intrinsic and extrinsic apoptotic signaling pathways.
• Drug Discovery & Screening: Serves as a reference compound and positive control in high-throughput screening (HTS) campaigns to identify novel caspase-7 inhibitors for therapeutic development.
• Biochemical Assay Development: Essential for developing and validating in vitro enzymatic assays to measure caspase-7 activity and inhibitor potency (IC50).
• Cell Biology Studies: Applied in cell-based models to study the functional consequences of caspase-7 inhibition on cellular fate and disease progression.
• Target Validation: A key pharmacological tool for confirming caspase-7 as a relevant therapeutic target in various disease models, including oncology.
• Diagnostic Reagent Component: May be utilized in the development of research-use-only (RUO) diagnostic kits for detecting apoptotic activity.

Basic Information

Product Name	Anti-Caspase-7
CAS No.	189258-14-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caspase-7 Inhibitor; Caspase 7 Inhibitor; Caspase-7 Selective Inhibitor; Apoptosis Inhibitor; ICE-LAP3 Inhibitor; CMH-1 Inhibitor; Mch3 Inhibitor; (S)-(+)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]isatin
EINECS	Contact for details

Quality Control

Our Anti-Caspase-7 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science research. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.