Description

3-Bromo-5-Fluorobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive aldehyde group and strategic halogen substitution points, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring specific halogenated aromatic units.
• Fluorescent Dye and Sensor Chemistry: Acts as a starting material for synthesizing fluorophores and molecular sensors due to its derivatizable aldehyde functionality.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl structures.

Basic Information

Product Name	3-Bromo-5-Fluorobenzaldehyde
CAS No.	188813-02-7
Molecular Formula	C7H4BrFO
Molecular Weight	203.01 g/mol
Synonyms	5-Fluoro-3-bromobenzaldehyde; 3-Bromo-5-fluorobenzenecarboxaldehyde; Benzaldehyde, 3-bromo-5-fluoro-; 1-Bromo-3-fluoro-5-formylbenzene; 3-Bromo-5-fluorophenyl aldehyde; 3-Bromo-5-fluorobenzene-1-carbaldehyde; 5-Bromo-3-fluorobenzaldehyde (isomer check required)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorobenzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material, ensuring traceability and compliance with global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.