Description

(E)-n-3-(Iodoprop-2-Enyl)2Beta-Carbomethoxy-3Beta-(p-Tolyl)-Nortropan is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel tropane alkaloid derivatives with targeted biological activity. It serves as a key building block for pharmaceutical companies and research institutions focused on developing new therapeutic agents for the central nervous system.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the pharmacological profile of new chemical entities.
• Process Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for studying synthetic methodologies and the chemistry of nortropane scaffolds.
• Bioconjugation & Probe Development: The reactive iodine moiety allows for potential use in creating labeled compounds for biochemical assays and diagnostic research.

Basic Information

Product Name	(E)-n-3-(Iodoprop-2-Enyl)2Beta-Carbomethoxy-3Beta-(p-Tolyl)-Nortropan
CAS No.	188680-71-9
Molecular Formula	C19H24INO2
Molecular Weight	425.31 g/mol
Synonyms	(E)-3-(3-Iodoprop-2-en-1-yl)-2β-methoxycarbonyl-3β-(4-methylphenyl)nortropane; 2β-Carbomethoxy-3β-(4-methylphenyl)-8-[(E)-3-iodoprop-2-en-1-yl]nortropane; (E)-8-(3-Iodoallyl)-2β-carbomethoxy-3β-(p-tolyl)nortropane; 3-Iodoallyl PICT; β-CIT iodoallyl analog; Nortropane derivative 188680-71-9
EINECS	Contact for details

Quality Control

Every batch of (E)-n-3-(Iodoprop-2-Enyl)2Beta-Carbomethoxy-3Beta-(p-Tolyl)-Nortropan is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.