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6-Fluoro-2-Methoxy-Nicotinic Acid CAS NO 188192-51-0


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CAS No.:188192-51-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Fluoro-2-Methoxy-Nicotinic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which introduces both fluorine and methoxy functional groups to enable precise modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning the properties of complex intermediates.

Application

  • Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral agent programs.
  • Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
  • Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals.
  • Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name 6-Fluoro-2-Methoxy-Nicotinic Acid
CAS No. 188192-51-0
Molecular Formula C7H6FNO3
Molecular Weight 171.13 g/mol
Synonyms 2-Methoxy-6-fluoronicotinic acid; 6-Fluoro-2-methoxypyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-fluoro-2-methoxy-; 188192-51-0; 6-Fluoro-2-methoxy-3-pyridinecarboxylic acid; 2-Methoxy-6-fluoro-3-pyridinecarboxylic acid; 6-Fluoro-2-methoxynicotinic acid
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Quality Control

Our 6-Fluoro-2-Methoxy-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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