Description

2-Ethoxy-5-Methylbenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, moisture-sensitive sulfonyl chloride derivative used as a key synthetic intermediate. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals. The product is supplied in a salt-free form to ensure optimal reactivity and consistency in sensitive synthesis processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require specific sulfonyl moieties for activity.
• Dye and Pigment Manufacturing: Serves as a precursor for creating sulfonated dyes and specialty colorants with enhanced properties.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of specialty monomers containing sulfone groups.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new organic reactions and material science.
• Ligand and Catalyst Preparation: Used to functionalize ligands and create novel organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Ethoxy-5-Methylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	187471-28-9
Molecular Formula	C9H11ClO3S
Molecular Weight	234.70 g/mol
Synonyms	5-Methyl-2-ethoxybenzenesulfonyl chloride; 1-Ethoxy-4-methyl-3-sulfonyl chloride benzene; 2-Ethoxy-5-methylbenzene-1-sulfonyl chloride; 4-Methyl-2-ethoxybenzenesulfonyl chloride; p-Tolyl-2-ethoxy sulfonyl chloride; (2-Ethoxy-5-methylphenyl)sulfonyl chloride; Benzenesulfonyl chloride, 2-ethoxy-5-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-5-Methylbenzenesulfonyl Chloride is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.