Description

Epothilone C CAS NO 186692-73-9 is a potent, naturally occurring macrolide compound belonging to the epothilone class, known for its microtubule-stabilizing properties. This compound serves as a crucial intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the oncology and life sciences sectors for drug discovery, mechanism of action studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel anti-cancer agents and other epothilone derivatives.
• Biochemical Research: Used as a reference standard and tool compound for studying microtubule dynamics, cell cycle arrest, and apoptosis mechanisms.
• Oncology Drug Discovery: Serves as a lead compound or a structural template for developing next-generation chemotherapeutic drugs with improved efficacy and reduced resistance.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in chemical biology, pharmacology, and medicinal chemistry.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and active pharmaceutical ingredients (APIs).
• Analytical Standard: Used for method development, validation, and quality control (QC) testing in analytical laboratories to ensure purity and identity of related substances.

Basic Information

Product Name	Epothilone C
CAS No.	186692-73-9
Molecular Formula	C27H41NO6S
Molecular Weight	507.68 g/mol
Synonyms	Epothilone C; 4,8-Dimethyl-12-(2-methyl-4-thiazolyl)-16-oxa-4,8-diazabicyclo[14.2.1]nonadeca-1(18),15(19),16-trien-5,9,13-trione; (-)-Epothilone C; Epothilone C, (-)-; (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
EINECS	Contact for details

Quality Control

Our Epothilone C is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material for analytical method development and validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the product label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.