Description

5-(Trifluoromethyl)Pyridin-3-Ol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring a trifluoromethyl group and a hydroxyl moiety on the pyridine ring, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for creating specialty polymers with specific electronic properties.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies.
• Liquid Crystal & OLED Materials: Potential intermediate in the synthesis of fluorinated components for electronic display materials.

Basic Information

Product Name	5-(Trifluoromethyl)Pyridin-3-Ol
CAS No.	186593-14-6
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	3-Hydroxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-pyridinol; 3-Pyridinol, 5-(trifluoromethyl)-; 5-Trifluoromethylpyridin-3-ol; 3-Hydroxy-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Pyridin-3-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.