Description

3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block distinguished by its unique halogen and trifluoromethyl substitution pattern. This molecular architecture is critical for imparting specific electronic and steric properties to advanced chemical intermediates, making it a sought-after reagent in sophisticated synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology, where the fluorine and trifluoromethyl groups enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides, with the halogen atoms contributing to potent biological activity and environmental selectivity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, due to its electron-withdrawing character and potential for fine-tuning material properties.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzaldehyde
CAS No.	186517-29-3
Molecular Formula	C8H3ClF4O
Molecular Weight	226.56 g/mol
Synonyms	2-Fluoro-3-chloro-6-(trifluoromethyl)benzaldehyde; 6-(Trifluoromethyl)-3-chloro-2-fluorobenzaldehyde; 3-Chloro-2-fluoro-α,α,α-trifluoro-o-tolualdehyde; Benzaldehyde, 3-chloro-2-fluoro-6-(trifluoromethyl)-; 186517-29-3
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality protocols and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.