Description

Euk-189 CAS NO 186350-27-6 is a specialized synthetic compound, also known as EUK-189, recognized for its role as a salen-manganese complex with superoxide dismutase and catalase mimetic activity. This compound is significant for its potent antioxidant properties, which are leveraged in advanced research and development. It is primarily needed by researchers and formulators in the pharmaceutical, biotechnology, and nutraceutical industries for applications in neuroprotection, anti-aging studies, and mitigating oxidative stress.

Application

• Pharmaceutical Research: Investigated as a therapeutic agent in models of neurodegenerative diseases, ischemia-reperfusion injury, and other conditions involving oxidative damage.
• Biochemical Research: Used as a tool compound to study cellular redox signaling pathways and the effects of reactive oxygen species (ROS).
• Cosmeceutical Development: Explored in high-end skincare formulations for its potential to protect skin cells from environmental oxidative stress.
• Nutraceutical Ingredients: Potential inclusion in advanced dietary supplements targeting cellular health and longevity.
• Academic & Institutional Research: Serves as a standard or experimental compound in university and government laboratory studies on synthetic antioxidants.
• Preclinical Development: Utilized in animal studies to evaluate efficacy and pharmacokinetics for new drug candidates.

Basic Information

Product Name	Euk-189
CAS No.	186350-27-6
Molecular Formula	C20H20ClMnN2O2
Molecular Weight	410.78 g/mol
Synonyms	EUK-189; EUK 189; EUK189; Salen-manganese complex EUK-189; Manganese 6,6'-((1E,1'E)-(1,2-cyclohexanediylbis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene))bis(2,4-dichlorophenolate); Chloro[(1E,1'E)-N,N'-bis(1-(2,4-dichlorophenoxy)ethylidene)cyclohexane-1,2-diamine]manganese; Manganese, chloro[(1E,1'E)-N,N'-bis[1-(2,4-dichlorophenoxy)ethylidene]-1,2-cyclohexanediamine]-
EINECS	Contact for details

Quality Control

Our Euk-189 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, identity confirmation by IR and mass spectrometry, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Brown to dark brown solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.