Description

Chimmitecan CAS NO 185425-25-6 is a synthetic, small-molecule compound belonging to the camptothecin class, recognized for its potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting topoisomerase I. It is primarily sought by advanced research institutions and pharmaceutical manufacturers engaged in oncology drug discovery and the development of next-generation chemotherapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced camptothecin analogs and novel anticancer drug candidates.
• Oncology Research: Used as a reference standard and active compound in biochemical and cellular assays to study topoisomerase I inhibition mechanisms.
• Preclinical Development: Serves as a critical starting material for the scale-up and process development of experimental oncology therapeutics.
• Academic Research: Utilized in university and institutional labs for investigating structure-activity relationships (SAR) within the camptothecin family.
• API Synthesis: An important precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) for clinical trials.

Basic Information

Product Name	Chimmitecan
CAS No.	185425-25-6
Molecular Formula	C24H23N3O5
Molecular Weight	433.46 g/mol
Synonyms	Chimmitecan; (S)-10,11-Methylenedioxy-20(S)-camptothecin; 7-(4-Methylpiperazinomethylene)-10,11-ethylenedioxy-20(S)-camptothecin; 10,11-Methylenedioxy-20-camptothecin; L-CPT; CPT; Camptothecin analog; Topoisomerase I inhibitor intermediate
EINECS	Contact for details

Quality Control

Our Chimmitecan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.