Description

2-(2-Fluoro-5-Pyridyl)-7-Azabicyclo(2.2.1)Heptane is a high-value, nitrogen-containing bicyclic compound featuring a fluorinated pyridine moiety. This advanced pharmaceutical intermediate is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics, where its unique scaffold offers significant potential for creating molecules with enhanced selectivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Preclinical Development: Employed in the production of compounds for pharmacological evaluation, toxicology studies, and early-stage formulation development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry research.
• Chemical Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(2-Fluoro-5-Pyridyl)-7-Azabicyclo(2.2.1)Heptane
CAS No.	185110-47-8
Molecular Formula	C11H13FN2
Molecular Weight	192.23 g/mol
Synonyms	7-Azabicyclo[2.2.1]heptane, 2-(2-fluoro-5-pyridinyl)-; 2-(2-Fluoro-5-pyridinyl)-7-azabicyclo[2.2.1]heptane; 2-(2-Fluoropyridin-5-yl)-7-azabicyclo[2.2.1]heptane; 185110-47-8; 2-(2-Fluoro-5-pyridyl)-7-azanorbornane; 7-Azabicyclo[2.2.1]hept-2-yl(2-fluoro-5-pyridyl)methane
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-5-Pyridyl)-7-Azabicyclo(2.2.1)Heptane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.