Description

Pyrazine-2-Sulfonyl Chloride CAS NO 184170-48-7 is a high-purity, reactive sulfonyl chloride derivative of pyrazine, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the pyrazine-sulfonyl moiety, enabling the creation of novel compounds with targeted functionalities. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in developing sulfonamide-based therapeutics, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate the pyrazine scaffold for enhanced bioactivity.
• Material Science Research: Employed in the development of advanced polymers, ligands for catalysis, and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules, facilitating proteomics research and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	Pyrazine-2-Sulfonyl Chloride
CAS No.	184170-48-7
Molecular Formula	C4H3ClN2O2S
Molecular Weight	178.60 g/mol
Synonyms	2-Pyrazinesulfonyl chloride; Pyrazine-2-sulfonyl chloride; 2-Sulfonylchloridopyrazine; Pyrazinyl-2-sulfonyl chloride; 2-Chlorosulfonylpyrazine; Pyrazine sulfonyl chloride; 184170-48-7; Pyrazine-2-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our Pyrazine-2-Sulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.