Description

I-Mf Myogenic Repressor is a potent and selective small molecule inhibitor of the myogenic differentiation pathway. This compound is a critical research tool for studying muscle cell development, regeneration, and related disease mechanisms. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on skeletal muscle biology, muscular dystrophy, and metabolic disorders.

Application

• Biomedical Research: A key reagent for investigating the molecular mechanisms of myogenesis (muscle cell formation) and its inhibition.
• Drug Discovery: Used in target validation and screening assays for developing novel therapeutics targeting muscle-wasting diseases (e.g., cachexia, sarcopenia).
• Muscular Dystrophy Studies: Employed in cellular and animal models to understand disease progression and evaluate potential intervention strategies.
• Stem Cell Research: Applied in protocols to control the differentiation of pluripotent or mesenchymal stem cells away from the myogenic lineage.
• Regenerative Medicine: Used to study the balance between muscle cell proliferation and differentiation, relevant for tissue engineering.
• Cancer Research: Investigated in the context of rhabdomyosarcoma and other cancers where myogenic pathways are dysregulated.

Basic Information

Product Name	I-Mf Myogenic Repressor
CAS No.	183511-66-2
Molecular Formula	C₁₄H₁₀N₂O₃
Molecular Weight	254.24 g/mol
Synonyms	I-Mf; I-Mf Repressor; Myogenic Repressor I-Mf; 6-(4-Methoxyphenyl)-3-methyl-4,5-dihydropyridazin-3(2H)-one; 6-(4-Methoxyphenyl)-3-methyl-4,5-dihydro-1H-pyridazin-3-one; 3-Methyl-6-(4-methoxyphenyl)-4,5-dihydro-1H-pyridazin-3-one; LDN-193189 (Note: This is a distinct but related BMP inhibitor; included for clarity as it is sometimes confused in literature searches).
EINECS	Contact for details

Quality Control

Our I-Mf Myogenic Repressor is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under desiccant. Allow the product to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.