Description

Am 251 CAS NO 183232-66-8 is a high-purity synthetic cannabinoid receptor antagonist used in advanced biochemical research. This compound is critical for studying the endocannabinoid system and its role in various physiological and neurological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, pharmacology, and drug discovery.

Application

• Pharmacological Research: Used as a selective CB1 cannabinoid receptor antagonist to investigate receptor function and signaling mechanisms.
• Neuroscience Studies: Essential for exploring the role of the endocannabinoid system in pain modulation, appetite regulation, and memory.
• Drug Discovery & Development: Serves as a reference standard and a key pharmacological tool in the development of novel therapeutics targeting cannabinoid receptors.
• Biochemical Assays: Employed in in vitro binding and functional assays to characterize new chemical entities and screen compound libraries.
• Academic & Clinical Research: Supports fundamental research into the therapeutic potential of modulating the endocannabinoid system for various disorders.

Basic Information

Product Name	Am 251
CAS No.	183232-66-8
Molecular Formula	C₂₆H₂₆ClN₃O₂
Molecular Weight	447.96 g/mol
Synonyms	AM-251; 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; CB1 Receptor Antagonist AM251; SR141716A analog
EINECS	Contact for details

Quality Control

Every batch of Am 251 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research applications. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.