Description

Methyl 5-(3-Fluorophenyl)Pyridine-3-Carboxylate CAS NO 181705-87-3 is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a pyridine core and a fluorinated aromatic ring, makes it an essential intermediate for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystal materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D Laboratories: Used in methodological studies and exploratory chemistry focused on cross-coupling and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Methyl 5-(3-Fluorophenyl)Pyridine-3-Carboxylate
CAS No.	181705-87-3
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	Methyl 5-(3-fluorophenyl)nicotinate; 3-Pyridinecarboxylic acid, 5-(3-fluorophenyl)-, methyl ester; 5-(3-Fluorophenyl)nicotinic acid methyl ester; Methyl 5-(m-fluorophenyl)nicotinate; 181705-87-3; Methyl 5-(3-fluorophenyl)-3-pyridinecarboxylate; 3-Carbomethoxy-5-(3-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(3-Fluorophenyl)Pyridine-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.