Description

L-Phenylalanine-13C6 is a stable isotope-labeled analog of the essential amino acid L-Phenylalanine, where all six carbon atoms are the 13C isotope. This high-purity labeled compound is critical for advanced research requiring precise metabolic and pharmacokinetic tracing. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as quantitative mass spectrometry and the development of internal standards.

Application

• Mass Spectrometry Internal Standards: Serves as a crucial quantitative reference standard in LC-MS and GC-MS analyses for accurate measurement of endogenous phenylalanine levels in biological samples.
• Metabolic Pathway Research: Used as a tracer to study phenylalanine metabolism, protein synthesis rates, and related disorders like phenylketonuria (PKU) in clinical and preclinical research.
• Pharmaceutical Development: Employed in the research and development of new drugs, particularly in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track drug metabolites.
• Nutritional and Biomedical Research: Facilitates studies on amino acid uptake, protein turnover, and the metabolic effects of diets in nutritional science.
• Stable Isotope Labeling (SIL): A key reagent for producing other 13C-labeled compounds, peptides, or proteins for advanced proteomics and metabolomics research.
• Quality Control & Method Validation: Essential for validating analytical methods in pharmaceutical quality control labs and forensic toxicology.

Basic Information

Product Name	L-Phenylalanine-13C6
CAS No.	180268-82-0
Molecular Formula	13C6H11NO2
Molecular Weight	~171.13 g/mol
Synonyms	(2S)-2-Amino-3-phenyl(13C6)propanoic acid; L-Phe-13C6; Phenylalanine-13C6; (S)-2-Amino-3-(phenyl-13C6)propionic acid; F-13C6; U-13C6-L-Phenylalanine; Phenylalanine (phenyl-13C6); L-α-Amino-β-phenyl(13C6)propionic acid
EINECS	Contact for details

Quality Control

Our L-Phenylalanine-13C6 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, chiral purity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (13C6)	≥ 99 atom % 13C
Chiral Purity (HPLC)	≥ 99.0% L-Isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.