Description

1-[[(2-Nitrophenyl)Amino]Carbonyl]-L-Prolyl-n-Methyl-3-(2-Naphthalenyl)-n-(Phenylmethyl)-L-Alaninamide is a complex, non-natural peptide derivative designed for advanced research and development. This compound serves as a critical building block or intermediate in the synthesis of novel bioactive molecules, offering unique structural features for modulating biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated peptide mimetics.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, especially protease inhibitors or receptor modulators.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptidomimetic Development: Serves as a core structure for creating stable peptide analogs with enhanced bioavailability and metabolic stability.
• Chemical Biology Probes: Employed in the design of activity-based probes for labeling and studying specific enzyme families in complex biological systems.
• High-Throughput Screening: Utilized as a reference compound or library component in screening assays to identify new lead compounds.
• Academic Research: Supports investigative studies in medicinal chemistry and organic synthesis at universities and research institutions.

Basic Information

Product Name	1-[[(2-Nitrophenyl)Amino]Carbonyl]-L-Prolyl-n-Methyl-3-(2-Naphthalenyl)-n-(Phenylmethyl)-L-Alaninamide
CAS No.	180046-99-5
Molecular Formula	C34H35N5O5
Molecular Weight	593.68 g/mol
Synonyms	N-[(2-Nitrophenyl)carbamoyl]-L-prolyl-N-methyl-3-(naphthalen-2-yl)-N-(phenylmethyl)-L-alaninamide; (S)-2-((S)-1-((2-Nitrophenyl)carbamoyl)pyrrolidine-2-carboxamido)-N-benzyl-N-methyl-3-(naphthalen-2-yl)propanamide; 180046-99-5; UNII-6I1J7F8W0F; 6I1J7F8W0F; SCHEMBL218090; ZINC000003869756; A peptide-based inhibitor intermediate.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to strict internal specifications aligned with cGMP principles where applicable, ensuring batch-to-batch consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.